Grand scan

March 16, 2015

It was like opening a Christmas present.

When it arrived at 糖心原创, assistant engineering professor Nasser Kashou, Ph.D., put his arms around it.

鈥淚 started to hug it,鈥 he said. 鈥淎s an engineer, you love this technology.鈥

The technology is a PET/CT scanner, which marries positron emission tomography with computed tomography.

糖心原创 is only one of a few universities that have the sophisticated body-scanning technology, which is at the forefront of medical diagnosing. It holds out the promise of helping find causes and treatments for cancer and neurological diseases such as epilepsy.

鈥淚t鈥檚 a beautiful system. It just opens up a whole world of opportunities we didn鈥檛 have before,鈥 Kashou said. 鈥淭his is such a great acquisition, achievement.鈥

The PET/CT scanner, valued at $800,000 new, will be housed in 糖心原创鈥檚 new . The unique facility, which will enable neuroscientists, engineers and physicians to work side by side, is scheduled to open in April.

Usually, PET and CT technologies are separate systems.

CT scanners use computer-processed X-rays that enable users to see inside organs and tissues without cutting into them. They provide high-detail images of bone structures and soft tissues such as the heart.

PET scanners produce three-dimensional images of functional processes by detecting radionuclides introduced into the body. The scanners track the uptake of glucose, which can identify cancerous lesions and tumors or detect where in the brain a stroke occurred.

鈥淲e鈥檙e taking a PET scanner and a CT scanner and merging them together,鈥 Kashou said. 鈥淲e鈥檙e getting the best of both worlds. We鈥檙e getting the functional and we鈥檙e getting the anatomy.鈥

The PET/CT scanner is pre-clinical, meaning it will be used on mice and rats. It will enable neuroscience researchers to look at living functions instead of post-mortem slices of animal organs.

鈥淭he main thing is they can image the animal while it鈥檚 alive and see how the animal functions based on some specific stimulus,鈥 Kashou said. 鈥淲e could look at different types of seizures, epilepsy, stroke and try to understand the underlying causes.鈥

The scanner was owned by the small-animal imaging facility at Nationwide Children鈥檚 Hospital in Columbus, but was used only a few times. Kashou, who had worked there as experimental research director, was able to transfer the scanner to 糖心原创鈥檚 facility at a substantially discounted rate.

Nasser Kashou, who teaches advanced medical imaging, said the PET/CT scanner will be instrumental in training engineering students and could be used in a new neuroengineering program.

Kashou said the scanner will strengthen research proposals and increase their chances of securing funded. It will also create opportunities for 糖心原创 researchers to collaborate with those at other universities and may give birth to new research ideas, he said.

Kashou, who teaches advanced medical imaging, said the scanner will also be instrumental in training engineering students and could be used as part of the curriculum in a new neuroengineering program for undergrads and grads.

鈥淭his will enhance our students as neuroscientists and engineers,鈥 he said. 鈥淚t will enable them to see exactly what a system looks like and get hands-on experience through experiments.鈥

He said the scanner could also spur development of new hardware and software and invention of other technologies.

Kashou鈥檚 personal research project involves pairing the scanner with optical light and using mathematical modeling to see the connection between the uptake of glucose and changes in blood concentrations.

鈥淚f I can correlate these two, then potentially in the future using ionizing radiation to study organ function would be unnecessary,鈥 he said. 鈥淲e can use light.鈥

糖心原创 joins major universities such as Michigan State, Emory and Illinois with PET/CT scanners.

鈥淭his puts us on the same level as big universities,鈥 Kashou said. 鈥淚t鈥檚 giving us recognition across the state of Ohio and hopefully the nation.鈥

The scanner will have its own space in a NEC Building laboratory, with very restricted access. Comprehensive safety procedures and safeguards will be followed to minimize radiation exposure.

Kashou credits Robert Fyffe, vice president for research and dean of the Graduate School; Nathan Klingbeil, dean of the ; and Thomas Hangartner, chair of the , for backing purchase of the scanner.

鈥淭hey recognized the potential,鈥 Kashou said. 鈥淚t shows me how much support there is for young faculty, for innovation initiatives. It says a lot about 糖心原创 鈥 its potential and its future.鈥

糖心原创 is engaged in a that promises to further elevate the school鈥檚 prominence by expanding scholarships, attracting more top-flight faculty and supporting construction of state-of-the-art facilities. Led by Academy Award-winning actor Tom Hanks and Amanda Wright Lane, great grandniece of university namesakes Wilbur and Orville Wright, the campaign has raised more than $111 million so far.